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Sherrel Howard Drugs of Abuse. Pharmacology and Molecular Mechanisms


Drug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience of drug abuse. Understanding the chemistry of commonly abused drugs and their impact on brain function will provide students and researchers with a more profound understanding of the molecular basis of drug abuse and addiction. Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse. Subsequent sections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how their chemical make-up interacts with brain function. The final chapter provides a brief overview of clinical substance abuse treatment. Providing a concise, accessible introductory overview of the topic, Drugs of Abuse: Pharmacology and Molecular Mechanisms will be a valuable resource for students, researchers, and others interested in how drugs interact with the brain. Introduces readers to the basic principles of neuroscience and pharmacology as related to drug use and abuse. Explores how the chemical make-up of drugs interact with the brain and can lead to addiction Includes coverage of a wide array of commonly abused families of drugs, including stimulants, depressants, hallucinogens, and others. Provides an essential introduction to the chemical and molecular underpinnings of drug use and abuse

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Giorgio Minotti Cardiotoxicity of Non-Cardiovascular Drugs


Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.

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Francesco Clementi General and Molecular Pharmacology. Principles of Drug Action


With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, all figures and tables from the book, and Power Point slides

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Michael Neal J. Medical Pharmacology at a Glance


Medical Pharmacology at a Glance is recognised as an excellent starting point for pharmacology study. This international best-seller is the perfect companion for all medical and health students, providing an accessible, visual overview of pharmacology. This 8th edition has been extensively updated, especially in the areas of anaesthetics, drugs used in AIDs, cardiovascular drugs, drugs used in anxiety, depression and schizophrenia, urological drugs, drug metabolism, as well as practical concerns such as drug indications and side effects. Ideal for USMLE and pharmacology exam revision, Medical Pharmacology at a Glance features: • The basic principles of drug action, interaction, absorption and excretion • Chapters based on diseases or syndrome, for efficient clinical learning • An emphasis on drug mechanisms • References to the pathophysiology of disease, to aid understanding of drug choice and action • Case studies with questions and full explanation of answers • A companion website at www.ataglanceseries.com/pharmacology featuring online cases and flashcards

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Y. Li Robert Cardiovascular Diseases. From Molecular Pharmacology to Evidence-Based Therapeutics


Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. • Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues

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Letizia Brandi Antibiotics. Targets, Mechanisms and Resistance


Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.

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Brian Fulton S. Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies


With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand complex neuroscience issues. The author illustrates medicinal chemistrys prominent role in treating addiction and covers specific drugs of abuse including narcotics, stimulants, depressants, nicotine, and marijuana. • Interprets complex neuro- biological and pharmacological information, like the drug-reward system, for medicinal chemists • Emphasizes neurotransmitters and neurochemical mechanisms of addictive drugs • Pulls together information on the many potential drug targets for treating addiction • Stresses unique medicinal chemistry problems when describing pharmacology testing methods and drug development

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Emanuela Corsini Molecular Immunotoxicology


The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.

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Anzenbacher Pavel Metabolism of Drugs and Other Xenobiotics


A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and «designer» drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

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Roosa Laitinen Molecular Mechanisms in Plant Adaptation


Plants are forced to adapt for a variety of reasons— protection, reproductive viability, and environmental and climatic changes. Computational tools and molecular advances have provided researchers with significant new insights into the molecular basis of plant adaptation. Molecular Mechanisms in Plant Adaptation provides a comprehensive overview of a wide variety of these different mechanisms underlying adaptation to these challenges to plant survival. Molecular Mechanisms in Plant Adaptation opens with a chapter that explores the latest technological advances used in plant adaptation research, providing readers with an overview of high-throughput technologies and their applications. The chapters that follow cover the latest developments on using natural variation to dissect genetic, epigenetic and metabolic responses of plant adaptation. Subsequent chapters describe plant responses to biotic and abiotic stressors and adaptive reproductive strategies. Emerging topics such as secondary metabolism, small RNA mediated regulation as well as cell type specific responses to stresses are given special precedence. The book ends with chapters introducing computational approaches to study adaptation and focusing on how to apply laboratory findings to field studies and breeding programs. Molecular Mechanisms in Plant Adaptation interest plant molecular biologists and physiologists, plant stress biologists, plant geneticists and advanced plant biology students.

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Sukhdev Chatu The Hands-on Guide to Clinical Pharmacology


Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect companion for students, doctors, nurses, pharmacists and other health care professionals who need help on the ward or are preparing for exams. It includes sections containing both treatment regimens of common conditions and detailed information on the relevant drugs that help you obtain a better understanding of therapeutic management. The benefits include: A-Z of over 100 key drugs in a one-drug-per-page format A systems-based approach Fully indexed text Clear explanations of drug mechanisms – a regular feature of pharmacology exams Management guidelines for common conditions within each system Brand new two-colour design to help with information retrieval A new chapter on chemotherapy agents Take the stress out of clinical pharmacology with The Hands-on Guide!

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Sukhdev Chatu The Hands-on Guide to Clinical Pharmacology


Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect companion for students, doctors, nurses, pharmacists and other health care professionals who need help on the ward or are preparing for exams. It includes sections containing both treatment regimens of common conditions and detailed information on the relevant drugs that help you obtain a better understanding of therapeutic management. The benefits include: A-Z of over 100 key drugs in a one-drug-per-page format A systems-based approach Fully indexed text Clear explanations of drug mechanisms – a regular feature of pharmacology exams Management guidelines for common conditions within each system Brand new two-colour design to help with information retrieval A new chapter on chemotherapy agents Take the stress out of clinical pharmacology with The Hands-on Guide!

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Javid Farideh Clinical Physiology and Pharmacology. The Essentials


This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students. Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students’ understanding of the physiology and pharmacology underpinning each case study scenario. 50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs. An essential revision text designed to help students apply their theoretical knowledge to real-life cases Realistic case studies focusing on commonly occurring conditions and diseases Model answers throughout Learning outcomes provided at the beginning of each chapter Key learning points presented in the cases follow each model answer Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses Reinforces major concepts and definitions Includes a glossary with a full list of drugs and disorders to support the text

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John Dickenson Molecular Pharmacology. From DNA to Drug Discovery


This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current – focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge – highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied – includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible – contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. A companion website with additional resources is available at www.wiley.com/go/dickenson/dnamolecular

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Ivor Ebenezer Neuropsychopharmacology and Therapeutics


Neuropsychopharmacology is a relatively new subject area in the neurosciences. It is a field of study that describes the effects of drugs from the molecular to the behavioural level and requires integration and synthesis of knowledge from various disciplines including neuroanatomy, physiology, molecular biology, pharmacology and the behavioural sciences. The principal aims of this book are to provide students with a clear understanding of CNS disorders, and an appreciation of how basic and clinical research findings can be translated into therapeutics. After an introduction to the subject area, the remaining chapters are focused on reviewing the main psychiatric and neurological disorders that are covered in most courses. They are discussed in terms of their clinical symptoms, epidemiology, pathology, aetiology, underlying neurobiological and neurochemical mechanisms, pharmacotherapy, adjunctive non-pharmacological treatments, and clinical outcomes. Each chapter of the book is a ‘stand-alone’ chapter and is written in a clear, accessible style. Written by an author with many years teaching and research experience, this textbook will prove invaluable for students of pharmacology, pharmacy and the medical sciences needing a truly integrated introduction to this exciting field.

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Sherrel howard drugs of abuse pharmacology and molecular mechanisms. Drugs of Abuse: Amazon.de: Sherrel Howard: Fremdsprachige ...

Bücher (Fremdsprachig) Wählen Sie die Abteilung aus, in der Sie suchen möchten.

Drugs of Abuse: Amazon.de: Sherrel Howard: Fremdsprachige ...

Bücher (Fremdsprachig) Wählen Sie die Abteilung aus, in der Sie suchen möchten.

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Drugs of Abuse: Pharmacology and Molecular Mechanisms by Sherrel Howard (2014-05-07) | Sherrel Howard | ISBN: | Kostenloser Versand für alle Bücher mit Versand und Verkauf duch Amazon.

Drugs of Abuse by Sherrel Howard · OverDrive (Rakuten ...

Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse. Subsequent sections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how their chemical make-up interacts with brain function. The final chapter provides a brief overview of clinical substance abuse treatment.

Drugs of Abuse von Sherrel Howard | ISBN 978-1-118-28845-0 ...

Drugs of Abuse von Sherrel Howard (ISBN 978-1-118-28845-0) bestellen. Schnelle Lieferung, auch auf Rechnung - lehmanns.de

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Drug abuse has been, and continues to be, a global societalissue with diverse sets of impacts. Drugs of Abuse: Pharmacologyand Molecular Mechanisms introduces the basic principles ofpharmacology ...

Sherrel Howard: Drugs of Abuse (PDF) - ebook download ...

Drugs of Abuse: Pharmacology and Molecular Mechanismsopens with a brief history of drug use and abuse. Subsequentsections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how theirchemical make-up interacts with brain function. The final chapterprovides a brief overview of clinical substance abusetreatment.

Sherrel howard drugs of abuse pharmacology and molecular mechanisms. Drugs of Abuse by Sherrel Howard · OverDrive (Rakuten ...

Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse. Subsequent sections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how their chemical make-up interacts with brain function. The final chapter provides a brief overview of clinical substance abuse treatment.

Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting


The proteins that gather light for plant photosynthesis are embedded within cell membranes in a site called the thylakoid membrane (or the «photosynthetic membrane»). These proteins form the light harvesting antenna that feeds with energy a number of vital photosynthetic processes such as water oxidation and oxygen evolution, the pumping of protons across the thylakoid membranes coupled with the electron transport chain of the photosystems and cytochrome b6f complex, and ATP synthesis by ATP synthase utilizing the generated proton gradient. The Photosynthetic Membrane: Molecular Mechanisms and Biophysics of Light Harvesting is an introduction to the fundamental design and function of the light harvesting photosynthetic membrane, one of the most common and most important structures of life. It describes the underlying structure of the membrane, the variety and roles of the membrane proteins, the atomic structures of light harvesting complexes and their macromolecular assemblies, the molecular mechanisms and dynamics of light harvesting and primary energy transformations, and the broad range of adaptations to different light environments. The book shows, using the example of the photosynthetic membrane, how complex biological structures utilize principles of chemistry and physics in order to carry out biological functions. The Photosynthetic Membrane: Molecular Mechanisms of Light Harvesting will appeal to a wide audience of undergraduate and postgraduate students as well as researchers working in the fields of biochemistry, molecular biology, biophysics, plant science and bioengineering.

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Харкевич Дмитрий Александрович Pharmacology. Textbook


The 2nd edition of the textbook is revised and supplemented with new information. Modern considerations concerning the bases of pharmacotherapy of certain diseases are being discussed. Mechanisms of drug action are reviewed according to the latest achievements in fundamental pharmacology. The textbook is designed for medical students.

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Botana Luis M. Therapeutic Targets. Modulation, Inhibition, and Activation


The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimers, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.

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Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting


The proteins that gather light for plant photosynthesis are embedded within cell membranes in a site called the thylakoid membrane (or the «photosynthetic membrane»). These proteins form the light harvesting antenna that feeds with energy a number of vital photosynthetic processes such as water oxidation and oxygen evolution, the pumping of protons across the thylakoid membranes coupled with the electron transport chain of the photosystems and cytochrome b6f complex, and ATP synthesis by ATP synthase utilizing the generated proton gradient. The Photosynthetic Membrane: Molecular Mechanisms and Biophysics of Light Harvesting is an introduction to the fundamental design and function of the light harvesting photosynthetic membrane, one of the most common and most important structures of life. It describes the underlying structure of the membrane, the variety and roles of the membrane proteins, the atomic structures of light harvesting complexes and their macromolecular assemblies, the molecular mechanisms and dynamics of light harvesting and primary energy transformations, and the broad range of adaptations to different light environments. The book shows, using the example of the photosynthetic membrane, how complex biological structures utilize principles of chemistry and physics in order to carry out biological functions. The Photosynthetic Membrane: Molecular Mechanisms of Light Harvesting will appeal to a wide audience of undergraduate and postgraduate students as well as researchers working in the fields of biochemistry, molecular biology, biophysics, plant science and bioengineering.

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George Billman Edward Novel Therapeutic Targets for Antiarrhythmic Drugs


Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs. Section Two addresses safety pharmacology, including the concept of «repolarization reserve,» safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs. Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets. Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids). Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.

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Mauricio Rojas Molecular Aspects of Aging. Understanding Lung Aging


Molecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches.

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Robert Blankenship E. Molecular Mechanisms of Photosynthesis


The classic and authoritative textbook, Molecular Mechanisms of Photosynthesis,is now fully revised and updated in this much-anticipated second edition. Whilst retaining the first edition’s clear writing style and accessible description of this complex process, updates now include cutting-edge applications of photosynthesis, such as to bioenergy and artificial photosynthesis as well as new analytical techniques. Written by a leading authority in photosynthesis research, this new edition is presented in full color with clear, student-friendly illustrations. An interdisciplinary approach to photosynthesis is taken, with coverage including the basic principles of energy storage, the history and early development of photosynthesis, electron transfer pathways, genetics and evolution. A comprehensive appendix, containing an introduction to the basic chemical and physical principles involved in photosynthesis, is also included. Molecular Mechanisms of Photosynthesis,second edition, is an indispensable text for all students of plant biology, bioenergy, and molecular biology, in addition to researchers in these and related fields looking for an accessible introduction to this vital and integral process to life on earth. stresses an interdisciplinary approach emphasizes recent advances in molecular structures and mechanisms includes the latest insights and research on structural information, improved techniques as well as advances in biochemical and genetic methods comprehensive appendix, which includes a detailed introduction to the physical basis of photosynthesis, including thermodynamics, kinetics, and spectroscopy associated website with downloadable figures as powerpoint slides for teaching

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Francis Martin Molecular Mycorrhizal Symbiosis


Recent years have seen extensive research in the molecular underpinnings of symbiotic plant-fungal interactions. Molecular Mycorrhizal Symbiosis is a timely collection of work that will bridge the gap between molecular biology, fungal genomics, and ecology. A more profound understanding of mycorrhizal symbiosis will have broad-ranging impacts on the fields of plant biology, mycology, crop science, and ecology. Molecular Mycorrhizal Symbiosis will open with introductory chapters on the biology, structure and phylogeny of the major types of mycorrhizal symbioses. Chapters then review different molecular mechanisms driving the development and functioning of mycorrhizal systems and molecular analysis of mycorrhizal populations and communities. The book closes with chapters that provide an overall synthesis of field and provide perspectives for future research. Authoritative and timely, Molecular Mycorrhizal Symbiosis, will be an essential reference from those working in plant and fungal biology.

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Minghan Wang Metabolic Syndrome. Underlying Mechanisms and Drug Therapies


This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.

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Minghan Wang Metabolic Syndrome. Underlying Mechanisms and Drug Therapies


This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.

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A. Knipe C. Organic Reaction Mechanisms 2010. An annual survey covering the literature dated January to December 2010


Organic Reaction Mechanisms 2010, the 46th annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2010. It details the latest progress in a wide range of classes of organic reaction mechanisms, including reactions of different compounds and acids and their derivatives, oxidation and reduction, aliphatic substitutions, elimination reactions, and molecular rearrangements, to name a few. An experienced team of authors compiled these reviews, ensuring the quality of selection and presentation.

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Rachel Airley Cancer Chemotherapy. Basic Science to the Clinic


This textbook is a clear and accessible introduction to the scientific and clinical aspects of the creation, development and administration of drugs or drug regimens used in the treatment of cancer. Unique in its approach, this book enables the student to gain an understanding of the pathological, physiological and molecular processes governing malignancy, whilst also introducing the role of health professionals and scientists in the research and treatment of cancer. The book consolidates all the essential information necessary for a full understanding of cancer chemotherapy, providing an informative, inexpensive and up-to-date coverage of the subject aimed at an undergraduate level readership. Key Features: Incorporates numerous diagrams, tables and illustrations to aid understanding. Examines key pharmacological and pharmaceutical issues such as dosing, toxicity and preparation of anti-cancer drugs. Includes a key chapter of practice essay questions to ease revision. Comprehensive coverage of drugs currently in pre-clinical and clinical development. An indispensable text for undergraduate students studying pharmacy and medicine as well as those doing courses such as molecular biology, biomedical sciences and pharmacology which cover aspects of oncology.

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Henry Brownstein H. The Handbook of Drugs and Society


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Lowe Robert C. Pocket Guide to GastrointestinaI Drugs


Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the worlds leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: Introduction of drug class Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations Dosing information for each GI condition and on- and off-label use Consistent use of both generic and trade names throughout Specific reference to drug use in pediatric patients and during pregnancy Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists.

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